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Systems Biology of Cancer [Hardcover]

Item : Systems Biology of Cancer [Hardcover]
Price : $168.99 (see below)
Category : Books
ISBN-10 ISBN-10 : 0521493390
ISBN-13 ISBN-13 : 9780521493390
Publisher Publisher : Cambridge University Press
Pages Pages : 548
Binding Binding : Hardcover
Item ID : 100116773

An overview of the current systems biology-based knowledge and the experimental approaches for deciphering the biological basis of cancer.Cancer is a complex group of diseases with many possible causes. Bringing together state-of-the-art contributions of international experts, Systems Biology of Cancer proposes an ultimate goal for the whole scientific community: exploiting systems biology to generate in-depth knowledge based on blueprints that are unique to each type of cancer.Cancer is a complex group of diseases with many possible causes. Bringing together state-of-the-art contributions of international experts, Systems Biology of Cancer proposes an ultimate goal for the whole scientific community: exploiting systems biology to generate in-depth knowledge based on blueprints that are unique to each type of cancer.With over two hundred types of cancer diagnosed to date, researchers the world over have been forced to rapidly update their understanding of the biology of cancer. In fact, only the study of the basic cellular processes, and how these are altered in cancer cells, can ultimately provide a background for rational therapies. Bringing together the state-of-the-art contributions of international experts, Systems Biology of Cancer proposes an ultimate research goal for the whole scientific community: exploiting systems biology to generate in-depth knowledge based on blueprints that are unique to each type of cancer. Readers are provided with a realistic view of what is known and what is yet to be uncovered on the aberrations in the fundamental biological processes, deregulation of major signaling networks, alterations in major cancers and the strategies for using the scientific knowledge for effective diagnosis, prognosis and drug discovery to improve public health.Contributors; Preface; Part I. Introduction to Modular Organization of the Networks of Gene Functions and Cancer: 1. Systems biology of cancer progression Sam Thiagalingam; 2. Lessons from cancer gls

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