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Renal Tumors of Childhood: Biology and Therapy [Hardcover]

Item : Renal Tumors of Childhood: Biology and Therapy [Hardcover]
Price : $173.99 (see below)
Category : Books
ISBN-10 ISBN-10 : 3662440024
ISBN-13 ISBN-13 : 9783662440025
Publisher Publisher : Springer
Pages Pages : 350
Binding Binding : Hardcover
Item ID : 100107487

This book provides a comprehensive overview of the biological basis of renal tumors in childhood and the clinical approaches to their treatment. Recent advances in our understanding of the molecular genetics of Wilms and other renal tumors are placed in their clinical context, including the differing treatment approaches of immediate surgery or pre-operative chemotherapy. The challenges in applying this knowledge to improve risk stratification and to incorporate biologically targeted agents into front-line therapy are discussed. All of the authors are experts from Europe and North America and the book has been written specifically as an easy reference for the practising clinician and the research scientist. It lays the basis for understanding the future direction of clinical and translational research to improve outcomes in patients with childhood renal tumors and will prove indispensable for those treating or researching into these diseases.Epidemiology of Renal Tumours of Childhood.- Genetic Predisposition to Wilms Tumour.- Clinical Presentation.- Pathology.- Treatment of Wilms Tumor in the Childrens Oncology Group.- Treatment of Wilms Tumor  The SIOP approach.- Treatment of Relapsed Wilms Tumor.- Imaging.- Biological prognostic pathways.- Molecular Targeted Therapy for Pediatric Renal Tumors.- Surgical Consideration For Wilms Tumours and other Neoplastic Renal Lesions.- Radiotherapy for Wilms' Tumour and other Childhood Renal Cancers.- Late effects and QOL.- Non-Wilms Pediatrci Renal Tumors.- Wilms Tumor in Low Income Countries.This book provides a comprehensive overview of the biological basis of renal tumors in childhood and the clinical approaches to their treatment. Recent advances in our understanding of the molecular genetics of Wilms and other renal tumors are placed in their clinical context, including the differing treatment approaches of immediate surgery or pre-operative chemotherapy. The challenges in applying this knowledge to improve risk stratifilÓ'

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