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Natural Product Biosynthesis: Chemical Logic and Enzymatic Machinery [Hardcover]

Item : Natural Product Biosynthesis: Chemical Logic and Enzymatic Machinery [Hardcover]
Price : $193.99 (see below)
Category : Books
Author Author : Walsh, Christopher T, Tang, Yi
ISBN-10 ISBN-10 : 1788010760
ISBN-13 ISBN-13 : 9781788010764
Publisher Publisher : Royal Society of Chemistry
Pages Pages : 785
Binding Binding : Hardcover
Item ID : 101302603

Authored by leading experts, this textbook provides a thorough description of the types of natural products, the biosynthetic pathways that enable the production of these molecules, and an update on the discovery of novel products in the post-genomic era. Appropriate to this modern era, the approach of this book is to codify the chemical logic that underlies each natural product structural class as they are assembled from building blocks of primary metabolism. This text will serve as a reference point for chemists, as well as for computational biologists, pharmacognocists, chemical ecologists, bioengineers and synthetic biologists.Authored by leading experts in the enzymology of natural product biosynthesis, this textbook provides a thorough description of the types of natural products, the biosynthetic pathways that enable the production of these molecules, and an update on the discovery of novel products in the post-genomic era.
Although some 500-600,000 natural products have been isolated and characterized over the past two centuries, there may be a 10-fold greater inventory awaiting immediate exploration based on biosynthetic gene cluster predictions. The approach of this book is to codify the chemical logic that underlies each natural product structural class as they are assembled from building blocks of primary metabolism.
This text will serve as a reference point for chemists of every subdiscipline, including synthetic organic chemists and medicinal chemists. It will also be valuable to bioinformatic and computational biologists, to pharmacognocists and chemical ecologists, to bioengineers and synthetic biologists.This is a long-awaited book since the advent of molecular biology tools for the investigation of secondary metabolism in the 1980s. A complete monograph addressing the biosynthesis of natural products (secondary metabolites) at the genetic and enzymatic level did not exist, although several books presented specific topics on the biosynthesis ols"

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