|Item||:||Mimicking the Extracellular Matrix: The Intersection of Matrix Biology and [Hardcover]|
|Price||:||$163.99 (see below)|
|Author||Author||:||Hudalla, Gregory A.|
|Publisher||Publisher||:||Royal Society of Chemistry|
Materials which are able to mimic the properties of the extracellular matrix are of great interest for many therapeutic and biomedical applications. Edited by leading experts in the field, this book brings together the current knowledge of extracellular matrix biology with the state-of-the-art of extracellular matrix-mimicking biomaterials. The book is suitable for both biologists and bioengineers interested in the extracellular matrix, and provides material scientists with a benchmark for future efforts to develop synthetic biomaterials as extracellular matrix mimics.Matrix biology: Extracellular matrix - Building function through complexity; Matrix biology: Gradients and patterns within the extracellular matrix; Matrix biology: ECM turnover and temporal fluctuation; Matrix biology: Structure assembly of maminin-rich matrices; Biomaterials: Incorporating ECM-derived molecular features in biomaterials; Biomaterials: Modulating and tuning synthetic extracellular matrix mechanics; Biomaterials: Protein interactions with glycosaminoglycan-based biomaterials for tissue engineering; Biomaterials: Spatial patterning of biomolecule presentation using biomaterial culture methods; Biomaterials: Controlling properties over time to mimic the dynamic extracellular matrix; Biomaterials: Supramolecular artificial extracellular matrices;
The extracellular matrix (ECM) is the focus of much interest in biology and bioengineering. Increasing understanding of the influence of the ECM on cell behaviour has led to the exciting possibilities of tissue engineering. Aside from new therapeutic tools, understanding the ECM is of course fundamental to basic cell biology research.
Mimicking the Extracellular Matrixapproaches this topic from both basic science and practical engineering perspectives. Seven topics are approached each in a pair of chapters, one with a biological approach and its partner with a bioengineering approach. Topics include the mechanical propertilC/
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