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Kinase Drug Discovery: RSC [Hardcover]

Item : Kinase Drug Discovery: RSC [Hardcover]
Price : $202.99 (see below)
Category : Books
ISBN-10 ISBN-10 : 1849731748
ISBN-13 ISBN-13 : 9781849731744
Publisher Publisher : Royal Society of Chemistry
Pages Pages : 332
Binding Binding : Hardcover
Item ID : 100408792

Kinase inhibition remains an area of significant interest across academia and in the pharmaceutical industry. There are now many marketed drugs which target kinases and a significant number of compounds are currently in various stages of clinical development. Although there have been a number of publications on kinase inhibition, this is the first to examine the future opportunities and challenges in targeting this important family of enzymes. The book is forward-looking and focuses on a number of key areas for kinase inhibition over the coming years.This is the first book to examine the future opportunities and challenges in the development of drugs which target kinasesDr Richard A Ward is a Computational Chemist, Oncology iMed, at AstraZeneca, UK. He received his BSc (Hons) in Chemistry with Bio-organic Chemistry at The University of Birmingham and gained a PhD in Computational Chemistry also at The University of Birmingham, under the supervision of Dr John Wilkie. His experience is in target selection, lead identification, lead generation and lead optimisation against kinase and non-kinase targets with specialisations in fragment-based lead generation along with library design and collection enhancement activities. He has publications in lead generation, virtual screening, druggability assessments, collection enhancement activities using computational ring enumeration along with reagent enhancement and has published supporting papers with a biological focus. He is also named as an inventor on a number of small molecule patents. Dr Frederick W Goldberg is a Medicinal Chemist at AstraZeneca, UK. He received his MSci (Hons) in Natural Sciences (Chemistry) at Cambridge University and then gained a PhD in Organic Chemistry at Imperial College, London, under the supervision of Dr Alan Armstrong. Subsequently he completed a Postdoc (AstraZeneca Fulbright scholarship) at the University of Texas at Austin, USA on Formal synthesis of Diazonamide A , under the supervision lj

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