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C-Type Lectin Receptors in Immunity [Hardcover]

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  • Category: Books
  • ISBN-10: 4431560130
  • ISBN-10: 4431560130
  • ISBN-13: 9784431560135
  • ISBN-13: 9784431560135
  • Publisher: Springer
  • Publisher: Springer
  • Binding: Hardcover
  • Binding: Hardcover
  • Item ID: 100054260
  • Seller: ShopSpell
  • Ships in: 2 Business day(s)
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  • Delivery by: Apr 25 to Apr 27
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The book presents the latest findingson C-type lectin receptors, focusing on individual receptors and theirsignaling. In recent years there have been great advances in the understandingof the function of these receptors as a newly emerging family of pattern-recognitionreceptors (PRRs) for pathogen-associated molecular patterns (PAMPs) anddamage-associated molecular patterns (DAMPs). Comprising four parts:ITAM-coupled Activating Receptors; HemITAM-bearing Receptors; ITIM-bearingReceptors; and Other Receptors and Related Topics, this comprehensive reviewcovers a broad range of C-type lectin receptors. The updated information onC-type lectin receptors and their ligands provided will appeal to a widereadership, from basic immunologists to physicians and surgeons. In addition,sections on novel drug development make this a valuable resource forpharmaceutical scientists.

Part 1 ITAM-coupled Activating Receptors.- 1Dectin-2 in anti-microbial immunity and homeostasis.- 2 The function of Mincleas a danger sensor.- 3 The DAP12-Associated Myeloid C-type Lectin 5A (CLEC5A).-Part 2 HemITAM-bearing Receptors.- 4 Dectin-1 (CLEC7A, BGR, CLECSF12).- 5 DNGR-1,an F-actin-binding C-type lectin receptor involved in cross-presentation ofdead cell-associated antigens by dendritic cells.- 6 C-type lectin-like receptor2 (CLEC-2).- Part 3 ITIM-bearing Receptors.- 7 Dendritic cell immunoreceptor(DCIR): An ITIM-harboring C-type lectin receptor.- 8 Regulation and Function ofthe Inhibitory C-type Lectin Clec12A/MICL.- Part 4 Other receptors and relatedtopics.- 9 DC-SIGN in infection and immunity.- 10 LOX-1 and immunity.- 11 MGL/CD301as a unique C-type lectin expressed on dendritic cells and macrophages.- 12 Structuralaspects of C-type lectin receptors.- 13 The Ligands of C-Type Lectins.

Sho Yamasaki, PhD, Professor at Kyushu UniversityThe book presents the latest findings on C-type lectin receptors, focusing on individual receptors and their signaling. In recenl#z

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