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Carbohydrate Chemistry: Volume 40 [Hardcover]

Item : Carbohydrate Chemistry: Volume 40 [Hardcover]
Price : $556.99 (see below)
Category : Books
ISBN-10 ISBN-10 : 184973965X
ISBN-13 ISBN-13 : 9781849739658
Publisher Publisher : Royal Society of Chemistry
Pages Pages : 670
Binding Binding : Hardcover
Item ID : 100055225

Volume 40 ofCarbohydrate Chemistry: Chemical and Biological Approachesdemonstrates the importance of the glycosciences for innovation and societal progress. Carbohydrates are molecules with essential roles in biology and also serve as renewable resources for the generation of new chemicals and materials. Honouring Professor Andr? Lubineaus memory, this volume resembles a special collection of contributions in the fields of green and low-carbon chemistry, innovative synthetic methodology and design of carbohydrate architectures for medicinal and biological chemistry.

Green methodology is illustrated by accounts on the industrial development of water-promoted reactions (C-glycosylation, cycloadditions) and the design of green processes and synthons towards sugar-based surfactants and materials. The especially challenging transformations at the anomeric center are presented in several contributions on glycosylation methodologies using iron or gold catalysis, electrochemical or enzymatic (thio)glycosylation, exo-glycal chemistry and bioengineering of carbohydrate synthases. Then, synthesis and structure of multivalent and supramolecular oligosaccharide architectures are discussed and related to their physical properties and application potential, e.g. for deepening our understanding of biological processes, such as enzymatic pathways or bacterial adhesion, and design of antibacterial, antifungal and innovative anticancer vaccines or drugs.

Lubineau's green synthons for carbohydrate chemistry; Recent Results in Synthetic Glycochemistry with Iron Salts; Conformationally locked sugars and analogs as inhibitors; The thiol-ene coupling; Exo-glycals as useful tools for anomeric functionalisation; Reactivity of allyl and vinyl pentosides in photo-initiated; Enzymatic thioglycosylation; Antigenicities roles of poly-N-acetyllactosamine-based sequences; A model synthesis of a mucin; Furano-specific enzymes; Liquid Crystal Glycolipids; Flexibility of C-Furanol√#

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